purpura its classification

purpura

purpura

Classification of purpuras

A- Purpura associated with normal numbers of platelets (non thrombocytopenic purpuras)

1- Vascular purpura

  a- Henoch-Schonlein purpura (anaphylactoid purpura).

  b- Meningococcemia or septicemia.

  c- Toxic vasculitis: may produce hemorrhagic rash as a reaction to drugs such as iodides.

  d- Viral or rickettsial infections.

  e- Scurvy (vitamin C deficiency).

2- Platelet function disorders

  a- Congenital platelet function defects (thrombasthenias).

  b- Acquired platelet function disorders: e.g. uremia.

  c- Drug-induced abnormalities of platelet aggregation (salicylates therapy).

B-  Purpura associated with decreased number of platelet (thrombocytopenic purpuras)

1- Idiopathic thrombocytopenic purpura (ITP).

2- Aplastic anemia.

3- Bone marrow infiltration e.g. leukemia.

4- hypersplenism.

5- Other thrombocytopenic purpura.

    a- Drug induced thrombocytopenia e.g carbamazepine.

    b- Congenital thrombocytopenic syndromes  (e.g. Wiskott Aldrich syndrome).

    c- Thrombocytopenia with cavernous hemangioma.

6- Neonatal thrombocytopenia.