Primary Biliary Cirrhosis its causes and treatment

      Cholestatic pattern of injury

–       only 10% of patients jaundiced at diagnosis

      Antimitochondrial antibodies

–       1:40 in 90% of patients, 1:80 >95%

–       May also be positive in :             
      Autoimmune hepatitis

      PSC

      syphillis

      myocarditis

      drug induced liver disease