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Sunday, February 2, 2014

Gastro-Intestinal Bleeding its causes and its treatment

* Upper GIT bleeding:
- Site of bleeding: is proximal to ligament of Treitz. (distal
duodenum)
- Presentation: - Haematemesis
- Melaena
- Occult blood in stool
* Lower GIT bleeding:
- Site of bleeding: is distal to ligament of Treitz.
- Presentation: - Heamatochezia (Bleeding per rectum)
- Melaena
- Occult blood in stool -
Haematemesis:
- Vomiting of blood
- Blood may be:
· red in color: if immediately after bleeding
· coffee ground (Melenemesis): when blood is in contact
with gastric acid for at least 1 hour.
* AE: Esophageal:
- Esophageal varices - cancer – Esophagitis
- Mallory – weiss tear
* Gastro-duodenal:
- Duodenal ulcer
- Gastric ulcer
- Gastritis
- Cancer stomach


* Systemic (general) causes:
- Haemorrhagic blood diseases.
- Haemorrhagic fever.
- Severe hypertension.
- Heparine therapy.
Mallory – weiss tear: mucosal tear due to repeated vomiting.
ttt : self limited, vasopressin may be used
*** D of haematemesis:
1- Clinical history:
Cause Question to detect I cause
1- O. varices
2- Peptic ulcer
3- Gastritis
4- Cancer stomach
5- Mallory-weiss
6- Coagulation defect
History of cirrhosis, confusion?
Epigastric pain, dyspepsia, heart burn?
History of drug intake e.g: Aspirin,
Alcohol, NSAID?
Epigastric pain?
Weight loss, Meat dyspepsia
Preceded by severe vomiting?
Oral anticoagulant?
History of cautaneous or orifice
bleeding?
2- Nasogastric tube: usually +ve for blood
3- Endoscopy to localize i site of bleeding.
4- Angiograpy: done if endoscope fails to show i site of bleeding.
5- Lab: Aneamia
­­ urea: (breakdown of blood)


* v of heamatemesis:
1- Resuscitation: IV fluid & blood transfusion if necessary.
2- Endoscopy
3- v of i cause: e.g: O. varices: 
peptic ulcer: IV omeprazole.
4- Iron therapy: given in chronic cases presenting with iron
deficiency anaemia.
D D of haematemesis:
- differentiation of i cause
- Heamoptysis
- False haematemesis: Ingestion of blood after bleeding from i
nose, mouth or pharynx then vomiting of this blood.
Melaena:
- Passage of black tarry stool due to presence of digested
blood.
- It indicates that heamorrhage has remained for ≥ 8 hours in
the GIT
* AE:
Site of bleeding: is not merely above ligament of Treitz but may
extended up to right colon.
So, AE of melaena =
i- AE if upper GIT bleeding (heamatemyesis)
ii- Jejunum & ileum: 2T + 2C
· Typhoid ulcer
· T.B enteritis
· Cancer head of pancrease
· Crohn's disease

iii- Colon:
· Rhight sided tumor
· Ulcerative colitis.
D D of dark stool:
- melaena
- Iron ingestion
- haemolytic Jaundice.
* Diagnosis & v of melaena; The same as
haematemesis
Haematochezia:
- Passage of bright red blood per rectum.
- Usually indicate that lesion distal to Rh. Colon
* AE:
- Hemorrhoids
- Diverticulosis.
- Colitis
- Colonic Cancer: usually present with chronic occult bleeding.


D of Haematochezia:
1- Clinical history
2- PR examination
3- Colonoscop
4- Barium enema
5- Nasogastric tube: -ve
6- Lab: Aneamia
Occult GIT blood loss:
- normal appearing stool
- hemoccult +ve
N.B: C/P of GIT hge:
1- C/P of i type of hge.
2- Hypovolemic shock
3- Recurrent GIT hge ® lead to iron deficiency anaemia.
4- C/P of i aetiology




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