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Saturday, February 1, 2014

Alcoholic Cirrhosis its causes and newest line of treatment

Aetiology:
Alcoholic cirrhosis usually develops after more than 10 years of
heavy drinking……………. How ?
1- Alcohal à ↓↓appetite & malopserption à nutritional cirrhosis.
2-
Direct Hepatotoxic
H Acetaldhyde
dehydrogenase
Alcohol Alcohol
¯
+ +
Pathology: - Path. Of cirrhosis itself (def.)
- Micronodular cirrhosis.
- Mallory bodies: Oesinophilic deposits.
Clinical picture:
1- C/P of cirrhosis itself. (LCF > pH)
2- C/P of i cause (Alchoholism)
3- History of prolonged alcohol intake > 10 y`
4- Acute alcoholic hepatitis à enlarged tender liver.
à vomiting
5- Other features of ch. alchohlism:
à GIT: Gastritis, hepatitis, pancreatitis, malabsorptions.
à CNS: Korsakow's syndromes: tremore, Amenesia.
à blood: haemolytic anaemia.
à Immune: recurrent infection.
à Metabolic: Hypoglycaemia, hyperlipidaemia.
à Bilateral parotid enlargement.
Investigation: general inv. For cirrhosis.
Treatment:
· Stop alcohol intake.
· General measures for cirrhosis.
· Essential aa - cholchiaia – cortisone
see the pictures

Alcoholic Cirrhosis

Alcoholic Cirrhosis

Alcoholic Cirrhosis

Alcoholic Cirrhosis

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