Agglutinate red cells
preferentially at low temperatures .
Agglutination is
reversible , but severe haemolysis can occur if the thermal range of the
antibody is high enough.
Reaction occurs in cold parts
of the body , leading to intravascular haemolysis , Raynaud’s and other vaso-
occlusive phenomena
Often associated with one of the following
Often associated with one of the following
Mycoplasma pneumonia .
Infectious mononucleosis .
Lymphoproliferative disorders .
. Paroxysmal cold haemoglobinuria is an
extremely rare forms .
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