Etiology
The infective stage is the mature larva-containing egg. Eggs are passed
in the feces of infected individuals and mature in 5-10 days under favorable
environmental conditions to become infective.
Pathogenesis
After ingestion
by the human host, larvae are released from the eggs and penetrate the intestinal wall before migrating to the
lung via the venous circulation. They break through the pulmonary tissues into
the alveolar spaces, ascend to the bronchial tree and trachea and are
reswallowed. Upon their arrival in the small intestine, the larvae develop into
mature adult worms.
Clinical manifestations
Clinical manifestations
1- Pulmonary ascariasis
2- Abdominal
ascariasis
Diagnosis
Treatment
- Albendazolel
(400 mg PO once for all ages), or
- Mebendazole
100mg twice daily for 3 days or 500mg once.
No comments:
Post a Comment