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Tuesday, February 25, 2014

Helminthic diseases Ascariasis: (Ascaris lumbricoides )

Etiology
 The infective stage is the mature larva-containing egg. Eggs are passed in the feces of infected individuals and mature in 5-10 days under favorable environmental conditions to become infective.
Pathogenesis
   After ingestion by the human host, larvae are released from the eggs and penetrate the    intestinal wall before migrating to the lung via the venous circulation. They break through the pulmonary tissues into the alveolar spaces, ascend to the bronchial tree and trachea and are reswallowed. Upon their arrival in the small intestine, the larvae develop into mature adult worms.
Clinical manifestations
1- Pulmonary ascariasis
2- Abdominal ascariasis
Diagnosis
Treatment
- Albendazolel (400 mg PO once for all ages), or
- Mebendazole 100mg twice daily for 3 days or 500mg once.


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