Etiology
· Humans are infected by ingestion of
embryonated eggs that are usually carried by fingernails, clothing, bedding or
house dust.
· Eggs hatch in the stomach and larvae
migrate to the cecal region where they mature into adult worms.
Clinical manifestations
Nocturnal anal pruritus and sleeplessness.
Diagnosis
Detection of eggs by adhesive cellophane tape pressed against the perianal
region early in the morning. Repeated examination may be needed and worms may
be seen in the stools.
Treatment
- Mebendazole 100mg as one dose and also
repeated after 2 weeks for all ages, or
- Single oral dose
of albendazole (400mg PO for all ages) repeated after 2 weeks, or
- Pyrantel pamoate
11mg/kg as one dose and repeated after 2 weeks.
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